PROGNOSIS OF ACUTE MYELOID LEUKEMIA HARBORING MONOSOMAL KARYOTYPE IN PATIENTS TREATED WITH OR WITHOUT ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION AFTER ACHIEVING COMPLETE REMISSION

Prognosis of acute myeloid leukemia harboring monosomal karyotype in patients treated with or without allogeneic hematopoietic cell transplantation after achieving complete remission

To evaluate the prognostic impact of korpskaft monosomal karyotype on post-remission outcome in acute myeloid leukemia, we retrospectively analyzed 2,099 patients who had achieved complete remission.Monosomal karyotype was noted in 73 patients (4%).Of these, the probability of overall survival from first complete remission was 14% at four years, wh

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A signaling pathway map of plasminogen activator inhibitor-1 (PAI-1/SERPINE-1): a review of an innovative frontier in molecular aging and cellular senescence

Abstract Plasminogen activator inhibitor-1 (PAI-1) is a vital regulator of the fibrinolytic mechanism and has been intricately involved in various physiological and clinical processes, including cancer, thrombosis, and wound healing.The PAI-1 signaling pathway is multifaceted, encompassing numerous signaling molecules and nodes.Recent studies have

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DIGITAL RECORDING AND NON-DESTRUCTIVE TECHNIQUES FOR THE UNDERSTANDING OF STRUCTURAL PERFORMANCE FOR REHABILITATING HISTORIC STRUCTURES AT THE KATHMANDU VALLEY AFTER GORKHA EARTHQUAKE 2015

On 25 April 2015, the Gorkha earthquake of magnitude 7.8, severely damaged the cultural heritage sites of welding sweater Nepal.In particular, the seven monument zones of the Kathmandu Valley World Heritage Site suffered extensive damage.Out of 195 surveyed monuments, 38 have completely collapsed and 157 partially damaged (DoA, 2015).In particular,

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Faith and Protest

This article considers the application of two counter-cultural issues of faith taken from a thirteenth century French manuscript to current issues of faith in South Africa.The thirteenth century French manuscript is a mystical click here treatise by Marguerite korpskaft Porete who was burned at the stake for her ideas of faith, and the current issu

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